Translational Technologies and Resources
Our mission is to support outstanding clinical investigation by facilitating analysis of biological samples and by assisting with acquisition and interpretation of laboratory data. We also support research that involves imaging and body composition measurements.
Services and Resources
The ITS Core Laboratory can assist clinical investigators with processing clinical samples from both diseased and control subjects. In addition to specimen storage, the laboratory offers a full range of assays and imaging services, as detailed below.
Imaging Lab Functions
The Core Laboratory oversees the usage of a GE Lunar iDEXA for measuring lean body mass and bone mineral density. A trained technician is available to perform these measures and provide guidance on analysis. This imaging technique is currently being used by a number of investigators for examining the impact of various nutritional and exercise interventions. The simultaneous acquisition of lean body mass and bone mineral density enhances the analytical value of iDEXA.
Magnetic resonance imaging is performed through the ITS-CRC and the Department of Radiology and has been used by many of our CRC investigators for determining muscle volume and fat changes associated with long-term interventions. Lower body imaging is particularly useful for studying leg muscle and fat changes associated with inactivity, the effect of anabolic agents in aging, and to evaluate pediatric and adult burn rehabilitation.
Contrast enhanced ultrasound for muscle perfusion
Contrast enhanced ultrasound (CEU) is an ultrasound technique performed during the infusion of a contrast agent, such as microbubbles, that is used to measure skeletal muscle microvascular perfusion. The ITS-CRC has a Phillips HDI-5000 ultrasound machine for applying this technique in humans.