ITS News & Events
The Institute for Translational Sciences (ITS) presents:
Topics in Translational Research
Posted 11/9/2009 - Grants & Publications
The next seminar in this new monthly series will be held Wednesday, November 18th 2009, in the Levin Hall South Auditorium from 4 to 5 pm. Featured speaker, Robert Rose, MD will present, Finding Answers to Big Questions: Overcoming disciplinary boundaries through research networks. Dr. Rose is Clinical Professor, Department of Psychiatry and Behavioral Sciences and Executive Director, Mind, Brain, Body and Health Initiative. A reception will follow from 5 to 6 pm in the Levin Hall Foyer.
For more information about the ITS, visit our website at: http://www.its.utmb.edu/
UCDC Core Labs Search Engine Demo
Posted 10/23/2009 - ITS
We have provided a link to the demo of the UCDC Core Labs Search Engine built by using Google Custom Search technology. This search is strictly limited to UCDC Core Labs web sites and it includes searching throughout the ITS web.
Topics in Translational Research Seminar Series Schedule
Posted 10/22/2009
- ITS
For your convenience the Institute for Translational Sciences has posted the schedule for the Topics in Translational Research Seminar Series. The schedule includes seven seminars which will be held at Levin Hall South 2.222 from 4pm - 5pm on the UTMB campus. Get the schedule now and prepare yourself for a wide range of topics in translational research.
Contacting the Coordination Core
Posted 10/1/2009 - Coordination Core
The Coordination Core provides ‘one-stop shopping' for investigators desiring to participate in translational research. You can phone us at x72872 (CTSA) or email us at CTSA@utmb.edu.
K12 Career Development Fellowships, Applications now being accepted.
December 5, 2008 - ITS awards Pilot Projects
ITS expands relationship with GenoLogics
Newsblaze, Aug. 12, 2008
UTMB’s Dr. Allan Brasier, director of the Sealy Center for Molecular Medicine, is quoted in this article that states that GenoLogics, a developer of translational research informatics software, has been selected by the center to collaborate on developing an integrated biomedical software solution. “The GenoLogics' vision to help clients conduct translational research by developing informatics solutions designed for this purpose was completely aligned with the centers strategic plan to connect our clinical and basic research areas,” Brasier said.
http://newsblaze.com/story/2008081205200300001.ew/topstory.html
Discovery of Molecular Phenotypes of Severe Asthma
Severe asthma is a chronic inflammatory disease characterized by relative resistance to corticosteroid therapy; these patients and constitute those with the greatest morbidity and admissions to the Intensive Care Unity. Previous work has shown that severe asthmatics show distinct patterns of cellular (neutrophilic) inflammation, and show evidence of impaired innate immunity. The severe asthma MTT measured panels of cytokines from bronchoalveolar lavage from 41 severe asthmatics vs. a matched group of nonsevere asthmatics. Using powerful unbiased bioinformatics analyses, distinct subgroups of asthmatics could be identified that significantly differ in lung function and dynamic responses to airway challenge solely based on hierarchical clustering of the BAL cytokine expression patterns. These investigators further sought as proof-of-principle to use the BAL cytokine panels to see if BAL cytokine patterns could predict which individuals were hyper-responsive to methacholine. This analysis involved predictive model building using a machine-learning technique of decision tree analysis, where methacholine hyper-responders could be identified and group into three distinct classes. These exciting findings indicate that protein signatures in BAL can be used for more accurate classification of asthma subtypes, thereby stimulating clinical research in personalized medicine. Use of molecular phenotyping information could lead to more robust identification of subgroups that may have distinct prognoses or be responsive to selective therapy.
The complete citation is found at: doi:10.1016/j.jaci.2007.10.015
For news release, see URL: http://blog.utmb.edu/newsroom/?p=3016
Events:
The Gulf Coast Consortium is hosting a number of workshops on the challenges for Personalized Medicine.
See http://cohesion.rice.edu//centersandinst/gcc/gcc_about.cfm?doc_id=12289 for more details.
